Orthopedic Conditions

Orthopedic Conditions
Stem cell therapy and regenerative medicine treatments have broad indications for patients with a whole spectrum of orthopedic and sports injury conditions. For example, NBA basketball star Stephen Curry had a PRP injection into his right knee for a grade one medial collateral ligament (MCL) sprain. Even golf superstar Tiger Woods recently underwent PRP treatment.

At Phenicell Regenerative Institute in Columbus, Ohio we proudly offer a comprehensive approach to treating a wide spectrum of orthopedic conditions. We use patients own Platelet-Rich Plasma (PRP) as well as their own stem cells from various sources. We guide our treatment by scientific research, common sense and patient's wishes, and we tailor the treatment to the individual. Phenicell Regenerative Institute also participates in clinical research to compare different techniques and commercially available products.

  • Knee pain

      Knee Pain
      Knee osteoarthritis (KOA) is the most common form of arthritis, which causes pain, stiffness, decreased function and is one of the leading causes of disability among adults. KOA is thought to be related to cartilage degenerative lesions secondary to inflammation related to hyperplasia and chondrocyte apoptosis. Also, with age, there is a decrease in subchondral blood vessels. This all leads to loss of elasticity, and joint fibrosis which leads to joint stiffness. Patients with KOA suffer both physical debilitation and physiological damage which leads to a poor quality of life. (Zhao, L, et al, 2018) Here at Phenicell, we have had good success in treating knee pain. We offer comprehensive therapeutic options including, Bracing, hyaluronic acid, PRP injection, autologous bone marrow stem cells from your own hip (BMAC), umbilical cord stem cells and most recently, stem cell derived exosomes.

    • Osteoarthritis of the knee

      Osteoarthritis of the knee
      There is clinical research at Harvard that injecting cryopreserved amniotic-derived stem cells is useful in treating patients with ostioarthritis (OA) of the knees (Vines et al, 2016).





    • Rheumatoid arthritis of the knee
    • Torn ligaments
      For example, medial lemniscus, lateral lemniscus, or anterior cruciate ligament (ACL) tears.
    • Knee bursitis
  • Shoulder Pain
      Shoulder Pain
    • Acromioclavicular (AC) separation
      A shoulder separation that results in pain with specific movements and potential tearing of ligaments.
    • Adhesive capsulitis (frozen shoulder)
      A recent case report showed that PRP injections for frozen shoulder improved pain, range of motion, and function of the affected shoulder (Aslani et al. 2016).
    • Rotator cuff injury
      Several studies have reported favored outcomes in surgically-repaired rotator cuff injury patients who are injected with stem cells, including a lower re-treat rate of the tendon (Giotis et al. 2017).
    • Subacromial bursitis
      A painful condition resulting from inflammation of a synovial cavity in the shoulder.
  • Rheumatoid arthritis

    Rheumatoid Arthitis
    There is clinical evidence that intravenous administration of adipose-derived mesenchymal stem cells in refractory rheumatoid arthritis has some benefit (Jose M Álvaro-Gracia, et al, 2016).



  • Carpal tunnel syndrome
    Phenicell Regenerative Institute treats patients with carpel tunnel syndrome in a comprehensive manner. We utilize every appropriate treatment method, including medication, physical therapy, bracing, PRP injections, and even surgery.
  • Lateral epicondylitis (tennis elbow)

    Tennis Elbow
    There is much evidence that PRP injections are useful in treating tennis elbow. There have been studies comparing PRP injections against steroid injections. This procedure might be covered by your insurance; please contact us for more information.


  • Medial epicondylitis (golfer's elbow)

    Golfers Elbow
    There is evidence that PRP injections help with the treatment of golfer's elbow, even in comparison to steroid injections.


  • Achilles' tendonitis
  • Plantar fasciitis

    Plantar Fasciitis
    Plantar fasciitis is one of the most common causes of heel pain. In a Randomized Controlled Trial in 2018, Sumit Kumar Jain's group compared 40 patient with plantar fasciitis treated with Platelet-Rich Plasma to 40 patients treated with corticosteroids and found similar results with respect to self-reported pain scales and the more objective Foot and Anke Outcome instrument core scale (FAI). Patients were followed for up to 6 months. However, treating patient with PRP instead of corticosteroids can avoid the well know side effects of steroids and yet still effectively treat the plantar fasciitis.

    Adriana E Jiménez-Pérez's group in 2019, compared the effectiveness and imaging changes (US and MRI) between PRP and corticoids injections for the treatment of chronic plantar fasciitis, using clinical results evaluated by the visual analogue scale (VAS), the AOFAS clinical rating system , and using imaging results (US and MRI). A single-centre, non randomized, prospective study of 40 consecutive patients (40 feet) with plantar fasciitis who had not responded to conservative treatment for at least 6 months was undertaken. The first 20 consecutive patients (group A) were treated with two local injections of 4ml of a PRP concentrate. The second group of 20 patients (group B) were injected with 4ml of 40mg methylprednisolone. score. Mean follow-up of 33 months. Imaging results were evaluated by plantar US after 3 and 6 months, and MRI after 6 months. There were no complications arising from the treatment. In group A (PRP group), the VAS changed from about 8 to about 2. In group B (steroid group), the VAS changed from about 8 to approximately 5 points. In the imaging tests, the thickness of the fascia in PRP group changed from 7.9mm to 4.8mm over 3 months following the injection, maintaining this thickness in the biannual controls. In steroid group the change was from about 8.mm to about 6 mm over 3 months, but then increasing to about 7mm after 6 months. This study suggests that the treatment of chronic plantar fasciitis by two injections of PRP is a safe, more efficient and long-lasting method than corticoid injections.

    References:
    1- Sumit Kumar Jain, et al: Foot Ankle Int. 2018 Jul;39(7):780-786. Comparison of Plantar Fasciitis Injected with Platelet-Rich Plasma vs Corticosteroids Comparative Study
    2- Adriana E Jiménez-Pérez et al: Foot Ankle Surg. 2019 Jun;25(3):354-360. Clinical and imaging effects of corticosteroids and platelet-rich plasma for the treatment of chronic plantar fasciitis: A comparative non randomized prospective study.